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Receptor

Search Result - 1

HMRbase accession number	20301
Swiss-prot Accession number	Q588Y6 (Sequence in FASTA format)
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B).
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	Phosphorylated (By similarity). Palmitoylated (By similarity).
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity).
Protein Length	389 Amino acids
Molecular weight	43372
Domain Name	7tm_1
References	1   Asahi D., Mori Y.; "Felis catus 5-hydroxytryptamine (serotonin) receptor 1B (Htr1b),mRNA."; Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	100144391
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	20537
Swiss-prot Accession number	Q7YSE7 (Sequence in FASTA format)
Description	Melanocortin 1 receptor.
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	317 Amino acids
Molecular weight	34718
Domain Name	7tm_1
References	1   Fukuzaki U., Kubo Y., Ishishita S., Tsuruma N., Takeuchi S.,Nishida-Umehara C., Ando J., Matsuda Y., Yamamoto H.; "Molecular cloning and chromosomal localization of the feline MC1Rgene."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	493917
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 3

HMRbase accession number	20779
Swiss-prot Accession number	Q9TST6 (Sequence in FASTA format)
Description	Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor).
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity).
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (By similarity).
Protein Length	474 Amino acids
Molecular weight	50533
Domain Name	7tm_1
References	1   Cully D.F., Tremml G., Zachwieja S.; "Felis domesticus beta adrenergic receptor subtype 1."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	493971
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 4

HMRbase accession number	20789
Swiss-prot Accession number	Q9TST5 (Sequence in FASTA format)
Description	Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor).
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity).
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity).
Protein Length	418 Amino acids
Molecular weight	46736
Domain Name	7tm_1
References	1   Cully D.F., Tremml G., Zachwieja S.; "Felis domesticus beta adrenergic receptor subtype 2."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	493767
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 5

HMRbase accession number	20800
Swiss-prot Accession number	Q9TST4 (Sequence in FASTA format)
Description	Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor).
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis (By similarity).
Protein Length	398 Amino acids
Molecular weight	41978
Domain Name	7tm_1
References	1   Cully D.F., Tremml G., Zachwieja S.; "Felis domesticus beta adrenergic receptor subunit 3."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	493930
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	20907
Swiss-prot Accession number	Q865E9 (Sequence in FASTA format)
Description	Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R).
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis (By similarity).
Protein Length	317 Amino acids
Molecular weight	34752
Domain Name	7tm_1
References	1  PubMed abstract 12620197 2  PubMed abstract 12620197
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 7

HMRbase accession number	21103
Swiss-prot Accession number	Q5GJ04 (Sequence in FASTA format)
Description	Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor).
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats.
Tissue Specificity	N/A
Post translational modification	N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity).
Function	Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity).
Protein Length	695 Amino acids
Molecular weight	78829
Domain Name	N/A
References	1   Neubauer K., Fickel J., Jewgenow K.; "Cloning and sequencing of cat FSH receptor cDNA."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. 2   Neubauer K., Fickel J., Jewgenow K.; "Cloning and sequencing of cat FSH receptor cDNA."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Hormone	Q52R91   Detail in HMRbase
Gene ID	554348
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 8

HMRbase accession number	21177
Swiss-prot Accession number	Q9BGN4 (Sequence in FASTA format)
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormonereceptor).
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 8 LRR (leucine-rich) repeats.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5) (By similarity).
Protein Length	763 Amino acids
Molecular weight	86588
Domain Name	N/A
References	1  PubMed abstract 11796491
Hormone	Q52R90   Detail in HMRbase    Q52R91   Detail in HMRbase
Gene ID	493842
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 9

HMRbase accession number	21254
Swiss-prot Accession number	Q53AD2 (Sequence in FASTA format)
Description	RecName: Estrogen receptor;ER;Alternative Name: Estradiol receptor;Alternative Name: ER-alpha;Alternative Name: Nuclear receptor subfamily 3 group A member 1;
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (By similarity).
Protein Length	595 Amino acids
Molecular weight	66050
Domain Name	Hormone_recep  Oest_recep  zf-C4
References	1  PubMed abstract 15955691
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	552888
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 10

HMRbase accession number	22193
Swiss-prot Accession number	Q6S9F0 (Sequence in FASTA format)
Description	Estrogen receptor alpha; Fragment
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	87 Amino acids
Molecular weight	10033
Domain Name	zf-C4
References	----
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 11

HMRbase accession number	22194
Swiss-prot Accession number	Q6S9F2 (Sequence in FASTA format)
Description	Progesterone receptor; Fragment
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	37 Amino acids
Molecular weight	4210
Domain Name	Prog_receptor
References	----
Hormone	Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 12

HMRbase accession number	22206
Swiss-prot Accession number	Q6V7J4 (Sequence in FASTA format)
Description	Estrogen receptor alpha; Fragment
Source organism	Felis silvestris catus (Cat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	78 Amino acids
Molecular weight	8891
Domain Name	Hormone_recep
References	----
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments